NutrientBuffer.com/hg has all the most extensive information on this product.

Nutrient Buffer® H/G is a U.S. Patented, drug free and veterinarian approved. It includes nutritional buffers, amino acid chelates, vitamins, minerals, GI soothing herbs, antioxidants, free radical scavengers, and probiotics designed to address hind gut ulcers, and reduce excessive intestinal permiability - which can cause neurological syndromes like EPM.

Intestinal Permiability

Horses with a history of upper gastric (stomach) ulcers have a much higher chance of developing intestinal ulcers soon after. Excess acidity tends to travel down to the gut from the stomach, and over time, causes the same problem in the intestines. If neglected, the trillions of protozoa and other parasites from the gut gain access to the body cavity of the horse where they can cause neurological syndromes and other chronic opportunistic infection(s) which can bog the immune system down dramatically.